
Apparently, the wrongs inflicted by England on Ireland remained a moral burden for him.

He had realised that Ireland’s claims, particularly Home Rule (demand for limited legislative autonomy), were to be met as a matter of principle and justice. In fact, the Irish problem was to span four of Gladstone’s ministries, diverting his attention from other issues. When he became Prime Minister for the first time (in 1868), William Ewart Gladstone, a Liberal leader and a giant of Victorian politics, declared, ‘ My mission is to pacify Ireland’.
